Sentence examples for mutation in organisms from inspiring English sources

Consequently, the per-generation rate of mutation in organisms with a large genome and a large number of germ-line cell divisions is very high, up to three orders of magnitude higher than, for example, in yeast [ 66- 69].

If the hypothesis of "missing schema element" is correct, we should expect a larger fraction of beneficial mutations in organisms with 20 genes than in organisms with 10 genes, since large-genome organisms should have more incomplete schemata that an additional gene can complete.

The taller column heights of transitional over transversional LOHs giving rise to MM-genotypes in Fig.  3a, b, and to a lesser extent in Fig.  3c, was in accord with the greater frequencies of transitional compared to transversional mutations in organisms.

Experimental induction of secondary mutation in model organisms such as bacteria and yeast has proven to be one of the most rewarding approaches to study gene function and regulation.

This bias likely occurs because mutations happening in organisms that have already reached a fitness potential plateau are much more likely to reduce fitness than increase it.

A random mutation in an organism, like a random change in any finely tuned machine, is almost always bad.

We established that H. salinarum NRC-1 mutS and mutL genes are redundant to an alternative system that limits spontaneous mutation in this organism.

Application of our instrument to larvae homozygous for a Tropomyosin mutant known to cause DCM in the adult fly reveals for the first time, to our knowledge, that an arrhythmia is associated with this mutation in this organism.

Experimental approaches for deciphering the function of human genes rely heavily on our ability to generate mutations in model organisms such as the mouse.

GeneChips are used widely today for performing tests such as detecting drug-resistance mutations in infectious organisms and monitoring human genes for cancer-associated mutations.

Traditional techniques for generating genetic mutations in most organisms have relied on selection from large pools of randomly induced mutations for those of particular interest, or time-consuming gene targeting by homologous recombination.