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While V600K is more frequently found in Australia with up to 20% of BRAF-mutated cases (Long et al, 2011) our population showed this mutation in only 8% and Schoenewolf et al (2012) did not find any case in a study population of 52 cases.
Presence of the JAK2V617F mutation in only 40% to 60% of patients with essential thrombocythemia (ET) underscores the heterogeneity of this myeloproliferative disorder (MPD).
This mutation was associated with a modest increase in pathogenicity in SPBNGA and SPBNGA-Cyto c, but not in SPBNGA-GA, which contained the mutation in only one of its two G genes and which remained non-pathogenic.
We detected this mutation in only one sample from the Urumqi Blood Center.
Consistently, in the current study, we observed BAP1 mutation in only 1 case of 49 examined.
P53 expression observed in BRCA1 luminal cases correspond to a true mutation in only four of seven cases [ 6].
Similar(39)
Mutations detected in only 42 clarithromycin-resistant strains were summarized in Table 3.
In all of the dogs with the disease, which causes whitish scales that darken with age, both copies of the gene were mutated; healthy dogs had mutations in only one copy or in neither.
Mutations in only a few genes are known to cause the development of severe obesity in early childhood [2].
The ironically named Universal Mutation Database covers mutations in only 34 genes, including LMNA.
Thus, it was shown that the synergistic effects of mutations in only two regulatory genes, acrR and marR, can significantly increase organic solvent tolerance in E. coli.
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