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Would you hire a bacteriologist, geneticist or oncologist who had no knowledge of the function of mutation in nature?
But the most frequent deleterious FRI mutation in nature is a 376 bp-deletion combined with a 31 bp-insertion in the promoter as observed in Landsberg erecta (FRI-Ler) [ 14, 21, 22].
Random mutation has also been proposed, in which a gene is replaced with a random value within certain lower and upper bounds, and may provide interesting insight into the mechanisms of mutation, since a small mutation in nature may cause a gene to take on a vastly different role.
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Board members told us that the new virus appeared less lethal than they first thought; the benefits of letting scientists around the world keep an eye out for the specific mutations in nature appeared greater than they first thought; and the risk that a terrorist would use the information seemed minimal, judging from a briefing they got from intelligence officials.
Third, there is a low frequency of these chance mutations in nature.
Does this observation imply that a large percentage of mutations in nature are advantageous?
Furthermore, our systematic search for tRNA switching events throughout the tree of life revealed the prevalence of tRNA anticodon mutations in nature.
These results require additional experimentation, with non-attenuated strains, to provide further evidence on the selective potential of these mutations in nature.
In addition, we have assessed the presence in wild populations of gene-TE chimeras identified using the genome sequence, to gain insight into the evolutionary forces acting on these mutations in nature.
Our search revealed the prevalence of tRNA anticodon mutations in nature, consistent with a response to novel translational demands as in our experimental evolution results", or something of the sort.
Our search revealed the prevalence of tRNA anticodon mutations in nature, consistent with a response to novel translational demands as in our experimental evolution results", or something of the sort. 1) The authors argue that overproducing low-copy tRNAs causes proteotoxic stress.
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