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A mutation in mutT2 was always associated with a mutation in muT4.
Thirty-nine of 43 W-Beijing strains with the mutation in mutT4 carried an additional mutation in mutT2 and in ogt.
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In KRAS-mutated samples, 20% had an additional mutation in PIK3CA.
Only 30,000 of more than 250,000 American women estimated to carry a mutation in BRCA1 or a related gene, BRCA2, have so far been tested.
About half of women who inherit a harmful mutation in BRCA1 or BRCA2 will develop breast cancer by the age of 70.
R544C mutation in exon11 was prevalent (45.0%).
The red characters indicate the SNP mutation in OsLAP6 gene.
After genetic counseling, germline testing for MMR (MLH1 and MSH2) gene revealed no mutation in MLH1 and p.G40S (GGC > AGC) mutation in MSH2 in heterozygote.
SW-13 is heterozygous for a mutation in p53 while H295R is wild-type for p53.
Genetic studies have identified a homozygous truncation mutation in Trak1 that causes hypertonia in mice.
The S228P mutation in βB1-crystallin has been linked to autosomal dominant congenital nuclear cataract.
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