Sentence examples for mutation in genotype from inspiring English sources

In order to widen the model scope, linear interaction energy was used as a tool for predicting activities of other genotypes based on the docked ligand poses while mutation binding energy was used to investigate the effect of each amino acid mutation in genotype 4. The model was applied for structure-based fragment hopping by screening a library designed by reaction enumeration.

PreS mutation in genotype C virus was more strongly associated with HCC than PreS mutation in genotype B virus.

The PreS mutation in genotype C virus is more strongly associated with HCC than the PreS mutations in genotype B virus [ 35].

Consistent with the much higher prevalence of G1896A mutation in genotype D than in A, genotype D is more likely to cause fulminant hepatitis than A. In Japan genotype B1 was found to pose a greater risk for fulminant hepatitis than genotype C2.

The majority of the HBeAg-negativity was as a result of the classical G1896A, which abolishes HBeAg expression [ 44] and occurs in genotype D or E but not A because the encapsidation signal secondary structure precludes this mutation in genotype A [ 45, 46].

Thus, the Fabaceae may be an excellent system to examine to what extent parallel changes in morphology are determined by parallel mutations in genotype, i.e. are the same genes mutated or do plants have many alternative genetic pathways for obtaining the same phenotype?

So it might be suitable to identify resistance mutations in genotypes that occur in minor proportions only.

Genetic changes arising by mutation in the genotype space are translated into phenotypic variance (phenotype space) depending on the structure of the genotype-phenotype map, and become exposed to selection.

However, about 63 million years ago a mutation in the genotype of the Old World primates resulted in the duplication of the gene for the long-wavelength opsin, which provided another channel for a trichromatic colour vision system.

The mutations found in genotype D or E isolates from HBeAg-negative individuals are shown in Figure  4: 15/49 genotype D or E isolates from HBeAg-negative sera, had wild-type BCP/PC region.

Second, some mutations in these genotypes produce genotypes where P new has higher penetrance.