Sentence examples for mutation in genomic from inspiring English sources

The presence of the heterozygous GR mutation in genomic DNA from fibroblasts of individual II.3 was confirmed.

For each class of non-synonymous variant - "missense", "nonsense", "nonstop" or "frameshift" -, all genes with at least one mutation in genomic and cell line DNA were determined, respectively.

TP53 is a tumour suppressor gene, and its mutation in genomic DNA causes many malignant diseases, including lung cancer (Breuer et al, 2005).

We also searched for the presence of this mutation in genomic DNA from another group of 912 lung cancer patients, 285 of them with familial cancer history and a cohort of 32 patients with other types of cancer.

However, the identification of a dual mutation in genomic DNA extracted from a pool of multiple cells does not necessarily mean that the two mutations are carried by a unique allele; they may correspond to two alleles in a single tumor clone or even to two individual tumor clones.

Taken together, we concluded that Pi7-J represented a new allele of Pi7 containing two silent mutations in genomic sequence.

Here we report a new method for the analysis of point mutations in genomic DNA through the integration of allele-specific oligonucleotide ligation assay (OLA) with magnetic beads-based electrochemiluminescence (ECL) detection scheme.

Additionally, two more genes were tested for mutations in genomic DNA.

We screened coding sequences from 39 genes for mutations in genomic DNA from a total of 261 resected, clinically annotated non-small cell lung cancer (NSCLC) specimens.

Chromatograms show MED12 mutations in genomic DNA in seven cases of fibroadenomas.

SSCP is an easy, but perhaps inefficient method to screen for mutations in genomic DNA.