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Myriad executives have said that when a European laboratory finds a mutation in either of the two genes, 20 to 40 percent of the time it does not know if the mutation raises the cancer risk.
Every mutant carried a mutation in either marR or acrR.
Cells with mutation in either TSC1 or TSC2 are hypersensitive to ER stress and undergo apoptosis.
A harmful mutation in either gene increases a woman's lifetime risk from 12% to about 60%.
Women who inherit a deleterious mutation in either of these genes have a very high lifetime risk of ovarian cancer (10 60%) and to some extent, increased risks of fallopian tube and peritoneal cancer.
The disease is caused by an autosomal dominant mutation in either of an individual's two copies of a gene called Huntingtin.
Similarly no effects were observed with a mutation in either cact or the adaptor protein myd88.
Sequence analyses of these genomic DNAs revealed no heterozygous mutation in either of the NOTCH2 exons (data not shown).
Conversely, 89.2% Taiwanese lung cancer patients have an identifiable mutation in either c-CBL, MET or EGFR or a combination of the three genes (Figure 2).
Our results indicated that individual mutation in either APP or PS1 alone is insufficient to trigger overtly compromised cardiomyocyte contractile function compared with concurrent presence of both.
Both dSETDB1 and SU VAR 3-9 collaborate in the region-3 germarium and a mutation in either of these genes causes localization of H3K9me3 away from DNA-dense regions in the region-3 cells.
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