Sentence examples for mutation in contrast from inspiring English sources

This clearly demonstrated the dominance of the s1 mutation, in contrast to the s* mutations, which are recessive.

Recent studies demonstrated greater sensitivity to platinum based chemotherapy for patients with p53 mutation, in contrast to previously believed [ 74].

This means that RPT5b Akita, RPT5b Bsch-0, RPT5b Sn5(1), and RPT5b Uk-4 alleles complement the rpt5a-4 mutatinn, in contrast to RPT5b Ws-4.

It is well established that BRAF mutation, in contrast to KRAS mutation, is associated with MSI [ 9, 10, 16, 33] and female sex [ 10, 33, 34], and our findings further validate this.

The distribution of mutations among the centromeres was highly skewed; a single centromere, CEN2, accumulated eight new mutations, CENR accumulated two mutations, and CEN5 acquired a single mutation; in contrast, TLO genes acquired 31 novel mutations in 13 ORFs analyzed across a total of 15,970 bp (average of 614 bp × 13 telomeres × 2 alleles).

Two common polymorphisms in regulatory sequences of the connexin40 (gene) gene have been reported to predispose to familial atrial standstill if they occur in conjunction with a SCN5A mutation, in contrast, carrying only a single genotype was relatively benign (Groenewegen et al, 2003).

To further study the role of bZIP1 in mediating the integration of N and L signaling, we studied the effect of a bZIP1 mutation in contrasted nutritional conditions of N and L combinatorial treatments.

As Kastritis et al. [12], we found a strong bias towards missense mutations, in contrast to truncating mutations, in APC and we could show that the mutation spectrum in UC differs significantly from the spectrum seen in colorectal cancer.

ANC1 deleted cells were slightly more sensitive than wildtype yeast to UV-induced point mutations and −1 framshift mutations; in contrast, UV-induced +1 frameshift mutations were similar between anc1Δ and wildtype.

MutS and DinB are proposed to play opposing roles in P. aeruginosa pathoadaptation: MutS acts in replication-coupled mismatch repair, which acts to limit spontaneous mutations; in contrast, DinB (DNA polymerase IV) catalyzes error-prone bypass of DNA lesions, contributing to mutations.

Nonsynonymous mutations, in contrast, are frequently subject to strong selection.