Sentence examples for mutation in conjunction from inspiring English sources

Although recurrent mutation in conjunction with mutation can maintain a polymorphism indefinitely at mutation-selection balance, here Ford is clearly interested in a more active role for natural selection in the maintenance of polymorphism.

Moreover, rtV173L was invariably found as a third compensatory mutation in conjunction with rtM204V and rtL180M in one of three patients who failed in lamivudine therapy, and it was not observed as a single change in chronic hepatitis B patients.

Vertebrate animals evolved these three gene families through birth-and-death evolution of repeated duplication and mutation, in conjunction with positive selection, to remove a staggering number of different foreign antigens in a highly specific fashion [ 11, 19].

Studies have found homozygous deletions of Smad4 in 30% of pancreatic tumors, and inactivating intragenic mutation in conjunction with loss of the other allele in another 20% of cases [ 36].

A third subject who carried a c.2delT mutation in conjunction with a pathologic but short (90) GAA repeat had disease levels in buccal cell (22%) with high control levels (157%) in blood.

Overall, genetic, cellular, and biochemical data indicate that most ciliopathies rather represent a continuum in which the phenotypic outcome is determined by the nature of the mutation in conjunction with the genetic background of the respective patient and oligogenic inheritance patterns.

Using extant dec-1 mutations in conjunction with genetically engineered dec-1 transgenes, we show that, although all three dec-1 proproteins, fc106, fc125, and fc177, are required for female fertility, gross morphological abnormalities in the eggshell are observed only in the absence of fc177.

We investigated MYD88 mutations in conjunction with cytogenetic study in 22 consecutive Korean WM patients.

As described in previous sections, the infinitely-many-sites model for mutations in conjunction with the simplified multi-locus haplotype model is assumed.

Consistent with the findings of Christianson and co-workers, we also identified H101N or -D and H126N or -Q mutations in conjunction with second-shell changes.

Mean length of the shorter GAA allele was 608 repeats, with 18 people carrying point mutations in conjunction with a single expanded allele.