If you have this mutation in both copies of the chromosome, you will have blue eyes for sure.
In 1945 Hershey and Luria, working independently, demonstrated the occurrence of spontaneous mutation in both the bacteriophages and the host.
We are interested in the role of the mismatch repair protein, Msh2 in the correction of a frameshift mutation in both yeast and mammalian cells.
Sickle cell disease is a recessive genetic disorder caused by a single mutation in both copies of a gene coding for beta-globin, a protein that forms part of the oxygen-carrying molecule hemoglobin.
A multigene hotspot mutational profiling of the BRAF, NRAS, HRAS and KRAS genes was carried out, and a shared G13R HRAS mutation in both the trichoblastoma and the sebaceous nevus components was found.
By multiplex-PCR we found 49 (40.5%), 21 (17.4%) and 10 (8.3%) isolates having AGC → ACC substitution in katG only, mutation in inhAC 15T only and mutation in both respectively.
When the team analyzed the patient's DNA, they found a mutation in both copies of the leptin gene.
Breast cancer patients with a mutation in both copies of the NQO1 gene have a 20% lower survival rate 5 years after treatment than do patients without the mutation, according to a new study of more than 2000 Finnish women.
Moreover the HML8 ORF was broken by a stop mutation in both transcripts.
Thus, the presence of the ace-1R mutation in both M and S forms probably resulted from introgression.
We hypothesise that mutation in both DISC1 and HTT impact on a common pathway underpinning major psychiatric illness.
