Sentence examples for mutation important from inspiring English sources

However, this collaborative study suggests that not only is the presence of a codon 12 glycine to valine mutation important for cancer progression but also that it may predispose to more aggressive biological behaviour in patients with advanced colorectal cancer.

From our analysis, mutations important for virus multiplication were not restricted to non-conserved residues (e.g. W75; Table 1; Figure 5 E and F).

Regarding coding mutations, important differences in the number of non-synonymous mutations were observed among candidates.

To determine if specific OCA2 residues are required for Cl− transport, we sought to identify mutations important for ion transport, but not melanosomal localization.

A key challenge in cancer genomics is to distinguish driver mutations, mutations important for cancer development, from random passenger mutations that have accumulated in somatic cells but do not have functional consequences.

A key challenge in interpreting these data is to distinguish driver mutations, mutations important for cancer development, from passenger mutations that have accumulated in somatic cells but without functional consequences.

Lewinsohn et al. identified five novel mutations including missense mutations within important functional domains, and splicing mutations predicted to result in truncated proteins from a family with MDS/AML (Lewinsohn et al., 2016).

The pattern of point mutation is important for studying mutational mechanisms, genome evolution, and diseases.

Random mutation was important, but environment — like the carcinogens in digestive waste — seemed to hold a modest edge.

The identification of the causal mutation is important for early diagnosis, clinical follow-up, and genetic counseling.

The identification of this MSH2 founder mutation has important implications for the design of mutation-detection strategies for the southern Chinese population.