Sentence examples for mutation heterogeneity observed from inspiring English sources

BRAF mutation heterogeneity observed in the primary melanoma cell line MMG1 strongly supports this conclusion.

This could be the basis for the phenotypic heterogeneity observed in families segregating mutations in SHH.

Given the phenotypic heterogeneity observed between different genetic mutations associated with familial AD [ 5], Acosta-Baena and colleagues' study of such a large number of individuals with the same mutation is a valuable addition to the literature.

These data indicate that the genetic heterogeneity observed in familial CCM may reflect mutation of different molecular members of a coordinated signalling complex.

The phenotype heterogeneity observed in human cardiomyopathy patients with identical mutations may be related to the ratio of mutant to wildtype transcript and protein, which may be a product of modifier genetic, epigenetic, transcriptional and post-transcriptional processes.

The absence of any other prospective mutation in the gene among 108 patients suggests that COMMD1 variants do not have any major contribution towards phenotypic heterogeneity observed in WD.

Heterogeneity observed between studies.

59 The heterogeneity observed in FH patients in relation to plasma LDLc levels and CHD has been suggested due to differences in the nature of the mutation in the LDLR and several studies have been published in support of this.

Phenotypic heterogeneity observed in tumours results from both genetic and non-genetic causes of heterogeneity.

Therefore, mapping altered genes into pathways promises to simplify tumor mutation heterogeneity for cancer therapies.

Substantial heterogeneity was observed (I=65%; p=0.02).