Sentence examples for mutation have the from inspiring English sources

Men with prostate cancer and an inherited gene mutation have the worst form of the disease, research reveals.

In particular, men with an MSH2 mutation have the highest risk for several types of cancers.

42 Individuals with an MSH2 or MSH6 mutation have the highest risk for endometrial cancer, with a lifetime risk of up to 44% (Table 1).

11 Individuals with an MLH1 or MSH2 gene mutation have the highest risks and the widest array of cancers attributable to Lynch syndrome.

ATP-binding mutation G334D almost completely abolishes the inhibitory effect of ATP [ 31, 32]; patients with this mutation have the most severe form of ND with developmental delay and epilepsy (DEND syndrome) [ 32].

Notably, carriers of MSH6 mutations appear to be particularly at risk of gastrointestinal cancer and EC, whereas carriers of an MSH2 gene mutation have the highest cancer risks across the spectrum, especially for the development of urinary tract cancer.

The mutation has the opposite effect of the one found in Colombia: people with the mutation are more likely to retain sharp cognitive abilities well into their nineties.

This is not surprising: the bigger the effect a mutation has, the bigger the chance that it will be something disruptive, so mutations that have dramatic effects are likelier to be harmful than mutations that produce modest changes.

By inserting copies of the DNA fragment into pigment-producing cells in a laboratory dish, they found that the mutation had the same effect, cutting melanin production, as human mutations did.

Among the three disease variants, the A53T mutation has the most subtle effect upon lipid binding.

However, the sob7-1 mutation had the opposite effect on flowering time in combination with phyA-211.