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The mutation has the opposite effect of the one found in Colombia: people with the mutation are more likely to retain sharp cognitive abilities well into their nineties.
This is not surprising: the bigger the effect a mutation has, the bigger the chance that it will be something disruptive, so mutations that have dramatic effects are likelier to be harmful than mutations that produce modest changes.
Should such an event occur in a germ line cell that will eventually produce a gamete, the mutation has the potential to be passed on to the organism's offspring.
If a protein can interact with some proteins in TGF-beta signaling pathway, its mutation has the potential to cause serious damage to the system.
Among the three disease variants, the A53T mutation has the most subtle effect upon lipid binding.
It is easy to see that the alternative mutation has the same effect on the order of the genes.
Similar(39)
By inserting copies of the DNA fragment into pigment-producing cells in a laboratory dish, they found that the mutation had the same effect, cutting melanin production, as human mutations did.
Men with prostate cancer and an inherited gene mutation have the worst form of the disease, research reveals.
However, the sob7-1 mutation had the opposite effect on flowering time in combination with phyA-211.
In particular, men with an MSH2 mutation have the highest risk for several types of cancers.
Of these three mutations, the yfjK mutation had the greatest effect when present alone in the Founder Δe14 background.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com