Sentence examples for mutation has previously from inspiring English sources

Exclusive generation of l-CD317 was achieved by mutating the M13 residue to an isoleucine (M13I); this mutation has previously been shown to prevent production of the s-CD317 isoform (Cocka and Bates, 2012).

To the best of our knowledge, only one clock gene mutation has previously been investigated in a CH population.

This mutation has previously been shown to render recombinant β3-containing GABAA receptors essentially insensitive to etomidate and propofol.

In particular, we identify a prominent role in the allosteric coupling for the Na+-coordinating residue D421, where mutation has previously been associated with neurological disorders.

The AKT1E17K mutation has previously been reported in breast, colorectal and ovarian cancer.

The N248D mutation has previously been reported in H1N1 human strains isolated in the thirties, forties, seventies, eighties and nineties.

The first mouse, with the p.Gln176* mutation, had previously been characterized without noting systemic effects [ 18].

Seven patients tested for a KRAS mutation had previously received chemotherapy, one was positive for a KRAS mutation and the remaining patients were negative.

We extended our investigations with a cohort of 60 patients with gliomas in which IDH1R132H mutation had previously been determined by DNA sequence analysis.

detected this mutation in three out of seven analyzed index patients, for whom only one disease-causing DYSF mutation had previously been identified using sequence analysis of all coding exons and flanking intronic boundaries.

The equivalent m.1624C>T MT-TV mutation, as well as the MELAS m.3243A>G MT-TL1 mutation, had previously been introduced into yeast mtDNA and the mitochondrial leucyl or valyl tRNA synthetase were each independently overexpressed.