Sentence examples for mutation has no from inspiring English sources

Although the G38G mutation does decrease the predicted mRNA stability relative to the ancestor, the A15A mutation has no effect on predicted mRNA stability (Supplementary Table 1), suggesting that changes in mRNA folding energy do not fully explain the effects of the substitutions.

Second, the facts that the I139 side-chain points toward A117 in the hydrophobic core and that side-chains of adjacent residues in a β-strand point in opposite directions, indicate that the I138 side-chain points away from the amyloid core such a topology provides a rationale for why the I138M mutation has no appreciable effect on the structure adopted by [hu] amyloid.

The results of in vitro liver tissue binding study shows that both the native protein and the mutant treatment displayed same degree green fluorescence, which indicate the mutation has no influence on the targeting capacity of the mu-IFN-CSP.

Surprisingly, this mutation has no detectable impact on protein synthesis in cells.

However, paradoxically, the GLE mutation has no effect on activity of the drop-out promoter which contains only downstream start sites.

Heterozygous and homozygous Rad1K185R mice were born at Mendelian ratios, indicating that the Rad1K185R mutation has no detrimental effect on mouse development (data not shown).

While the inheritance of a maternal Tsix deletion results in embryonic lethality during post-implantation development around d9.5, inheritance of a paternal Tsix mutation has no effect in female embryos (Lee 2000; Sado et al. 2001).

The methodology is based on the existence of synthetic-lethal relation between pairs of genes: two genes are synthetically lethal if their simultaneous mutation leads to inviable organism, while their separate mutation has no substantial effect on the organism's fitness.

However, using the dead end complex assay we demonstrated that the K65R mutation has no obvious effect on dADP binding (Fig. 3B), suggesting that the substitution instead directly affects catalysis.

The E466K mutation has no effect on Mint binding instead causing an enhanced affinity for Rab3 [10] and increasing the number of exocytotic events [29].

First, the BoxG18A mutation has no significant effect during competition for UDP-GlcNAc, which is the end product of GlmS and GlmU activities.