Sentence examples for mutation has increased from inspiring English sources

The frequency of isolates with the H274Y mutation has increased with each flu season, including in countries that do not regularly prescribe oseltamivir [2], [5] [7].

The number of children identified as harboring this mutation has increased with improved clinical testing.

Our data are consistent with the working hypothesis that the CUL3Δ403 459 mutation has increased structural flexibility.

Since the 1920s the incidence of breast cancer has increased fourfold, and interestingly the penetrance of the BRCA2 founder mutation has increased from 20%to80%0% during this time period, indicating an effect of lifestyle not only on sporadic but also on genetic breast cancer.

This result was expected as the Hampshire RN- pigs carrying the R225Q γ3Amutationtion have increased muscle glycogen content [26].

At this time, the M184I mutation had increased from 0.08% to 0.27% in patient 2 and from 0.08% to 63% in patient 5 (Fig. 1).

Mice homozygous for the point mutation have increased muscling even though their circulating levels of myostatin protein are dramatically increased, consistent with an inability of myostatin to be activated from its latent state.

CHO and COS-7 cells transfected with the A673V mutation have increased secretion of Aβ11 40, Aβ11 42 and Aβ3[pE] 42 compared with controls transfected with wt APP; however, within the limits of uncertainty, levels of Aβ1 40 and Aβ1 42 were also increased by the same ratio [39].

These data show that tumors harboring the MEK1 T55delinsRT mutation have increased local invasion and therefore likely have a higher propensity to spread to distant organs.

This is in accordance with our results showing that patient 1 with the PTPRT mutation had increased phosphorylation of STAT3 and activation of STAT3 responsive genes.

It is well established that families carrying a germline BRCA1 mutation have increased incidence of basal-like/triple-negative breast cancers, while germline BRCA2 mutations predispose to cancers of the lumB subtype [ 22- 24].