The research showed that many ominous mutations happen spontaneously, meaning they are not passed down from one generation to the next; and such mutations happen more often in tissues that divide often.
If two genotypes, for example one with the nucleotide G and another with the nucleotide A in the same position, have the same fitness, but mutation from G to A happens more often than mutation from A to G, then genotypes with A will tend to evolve.
CFLD happens more frequently in males, in patients with severe mutations, and in patients with pancreatic insufficiency, with a poor nutritional status, and with a history of neonatal meconium ileus.
"It happens more and more.
"It happens more with reading.
The trend both left and right is that under 4×4 mutation more of the 20×20 replacements would happen more frequently than under 64×4 mutation.
The group's analyses and computer simulations looking at how 370A arose and spread indicate that the mutation creating the variant gene happened more than 30,000 years ago in central China.
Instead, resistance evolves because random mutation happens to generate some individuals that are better able to survive the antibiotic, and these individuals can reproduce more than other, leaving behind more resistant bacteria.
The smaller the probability, the less likely a mutation happens.
"Things happen more organically.
