Sentence examples for mutation groups from inspiring English sources

The Dendrix algorithm, which has been applied to the analysis of different cancer types in TCGA study, was able to identify 8 mutation groups mutated in 94% of patients from 17 cancer types and groups of mutually exclusive genes in lung adenocarcinoma and glioblastoma multiforme.

Among p53 carriers, cancer risk was significantly higher in females than in males, but no difference in cancer risk was found between missense and truncating mutation groups.

We observed a slight decrease of luciferase activity after a 3-MC treatment in the two PPRE mutation groups, but this decrease is not significant.

However, we found no discrepancy between the two p53 mutation groups, possibly due to insufficient statistical power.

Patients were categorised into established mutation groups according to their genotype with the less severe mutation determining the group (9).

Here we summarize typical and atypical presentations of specific mutation groups and discuss some of its implications.

Seven of the 10 CNC cases which included the PRKAR1A genetic test showed PRKAR1A genetic mutation (Table 3), and these patients were younger than those without the mutation (mutation group 26.6 ± 20.2 years old, no mutation group 64.3 ± 11.7 years old, p = 0.0339).

For example, for genes KDR and MAPK1, their correlation coefficient is 0.63 in p53 normal group, but 0.01 in the p53 mutation group.

For the four identified gene pairs, they show strong positive correlations in the normal group, but lower negative or no clear correlation in the mutation group, as shown in Figure 1.

This signature was shared, in part, with the SHOC2 mutation group, while it noticeably diverged in the SOS1 mutation group.

The SOS1 mutation-associated signature appeared oppositely modulated in the SHOC2 mutation group, while it was relatively conserved among samples of the PTPN11 mutation group.