Sentence examples for mutation given a from inspiring English sources

It turns out that quite a wide range of landscapes satisfy the condition (at least trivially) under point mutation given a sufficiently low mutation rate, while the property appears to be difficult to satisfy under genetic recombination.

From a cohort of 3 000–6 000 children, we anticipate that 6 12 children will have the m.1555A > G mutation, given a mutation frequency of 1 in 526 (95% CI 1 in 357 to 1 in 770) [ 14].

A mutation gives a person about a 60percentt chance of getting the disease.

Directly estimating the penetrance of the deafness mutation gave a probability that an individual ear was deaf in a dog with the homozygous deaf genotype of 0.47.

This would result in the c1A>G mutation giving a similar truncated protein to the c2T>C mutation.

Yellow highlighting indicates that the mutation gave a lethal phenotype in yeast at 25°C.

One breast cancer patient carried the Norwegian founder mutation, giving a point estimate of the frequency of 0.2%95%5% CI 0.01-1.20.01-1.2%

Previous studies suggesting that the A88V mutation gave a gain of function in Cx26, examined hemichannel function in the absence of extracellular Ca2+ (Mhaske et al., 2013).

This mutation serves two purposes in the experimental setup: (1) the gain of function mutation gives a larger concentration window to probe effects of introduced mutations and (2) the pore mutation causes differences in rectification between the two stoichiometries, which can be probed via voltage jump experiments to confirm which stoichiometry is being observed.

Here we present a modified version of SIFT called Bi-directional SIFT (B-SIFT) which is able to identify both deleterious and a subset of activating mutations given a protein sequence and a query mutation within that sequence.

Jessica Queller's article about BRCA mutations gives a compelling look into the quandaries faced by women who are (or might be) carriers of these genetic predispositions to breast cancer.