Sentence examples for mutation generating the from inspiring English sources

The parameters d and e represent the mutation's sex-specific penetrance, that is the likelihood of the mutation generating the respective enhancing or repressing phenotype.

Use of linkage-disequilibrium (LD) information increases the precision of QTL mapping because it exploits the entire number of recombinations accumulated since the original mutation generating the new QTL allele occurred [ 13].

The E682K mutation generated the same amounts of Aβ1 42 but significantly less Aβ1 40, leading to an increased Aβ1 42/Aβ1 40 ratio.

Recombination combined with mutation generates the different selected haplotypes that contain some segments of the ancestral haplotype.

RT-PCR of cDNA from the patient heterozygous for the mutation generated the expected WT product plus an additional band that corresponded to the size of the predicted alternative product (425 bp; Fig. 2C).

Our data do not allow us to determine the regulatory nature of the mutations generating the observed covariances.

These mutations generate the mutant lamin A proteins progerin and FC-lamina A, respectively, which cause nuclear deformations and chromatin perturbations.

However, neither the −57A/C nor the −146C/T mutation led to an increase in TERT transcription, despite the fact that these mutations generate the same putative ETS-binding motif of TTCCGG.

These mutations generate the CYP2E1 wild (c1) allele and the less common (c2) allele and have been reported as conferring higher risk for developing oral, pharyngeal [ 7] and lung cancer [ 8].

The simulation provides the branch where the mutation generating each SNP occurred.

A scheme of the mutation generated in the nodD3, nodD4 and nodD5 genes are shown in Fig.  1.