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Unsupervised cluster analysis of the 293 genes largely separated ZG, ZF, and APA of patients with a KCNJ5 somatic mutation from those without.

It was not possible to distinguish patients with a GLUD1 mutation from those with a HADH mutation based on these two features.

Again, unsupervised cluster analysis of these 210 genes mostly separated ZG, ZF, and APA from patients with a KCNJ5 somatic mutation from those without.

In fact, an allele separated by a single mutation from those typical of P. muralis alleles, which in turn are distinct by several mutations from the ingroup, was detected in an individual with P. hispanica type 3 mtDNA.

Although unsupervised cluster analysis did separate ZG, ZF, and APA with a KCNJ5 mutation from those without, only 9 upregulated ZG genes identified had previously been documented involvement in aldosterone synthesis pathway.

Similar(55)

We identified a series of potential driver mutations from those genes frequently mutated in bladder cancer in the COSMIC [ 14] and ATLAS [ 15] databases (as of October 1st, 2014).

Single-cell mutational analysis of CTCs has also revealed different mutations from those found in the same patient's primary and metastatic tumors; however, targeted ultra-deep sequencing revealed the presence of matching mutations at subclonal levels despite being initially missed, suggesting that only some primary or metastatic tumor cells transition into CTCs that cause tumor progression [ 4].

Transgenic models should be able to (4) discern pathogenic effects of familial forms (FAD) mutations from those of transgene overexpression.

The classification tree built using the breast cancer data separated tumors with BRCA1 mutations from those with BRCA2 mutations, with sporadic tumors separated from both groups and from each other.

However, among SIOD patients with SED, no radiographic features distinguish those with SMARCAL1 mutations from those without SMARCAL1 mutations.

These data sets and models provide an effective means of separating true viral mutations from those erroneously introduced during sample processing and sequencing.

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