Sentence examples for mutation frequency when from inspiring English sources

Specifically, this study evaluated the contribution of type 2 polymerase to mutation frequency when measured by the tk mutagenesis and non-HSV DNA mutagenesis assays.

Furthermore, TIVAR + bacteria exhibited an additional ~ 5-fold increase in mutation frequency when derived from treated (day 7) versus untreated (day 5) mice (P < 0.001).

Although the potential contribution of this supercoiling-induced phenomenon to modulate mutation frequency during viral replication is unclear, it could partially explain why the type 2 polymerases confer a high mutation frequency to HSV-2 genomes and a low mutation frequency when placed within an HSV-1 genome.

Mutation frequency increased when the quantity of injected Hox5-sg1 was increased from 1.5 to 3.0 pg.

Hopwood et al. (1985) showed that mutation frequency is higher when the survival rates from UV mutation are between 10 and 0.1%%.Since the aim of this work was to increase the innate capability of the strain to secrete/produce more cellulases, 2-DG, an antimetabolite, was used to screen for catabolite repression-resistant mutants (Montenecourt and Eveleigh 1975).

In E. coli (LM102), insertion of M1dG resulted in a targeted mutation frequency of 18% (when corrected for strand bias) (8).

Furthermore, in some cases, an open chromatin state induced by transcription can increase the mutation frequency, as seen when somatic hypermutation in the heavy chain locus correlates with transcription (Yoshikawa et al. 2002).

Pair-wise analysis showed that for strains of 9a5c, Ann1 and Dixon, the lowest mutation frequency was obtained when each of them was compared with Temecula-1, which indicates a closer phylogeny relationship of these strains to Temecula-1.

We found that among the 1528 genes that are conserved in all the four strains, the Temecula-1 gene set had the lowest mutation frequency (Table 2) when compared to the other three strain sets, suggesting that Temecula-1 had diversified at a slower rate.

Our rationale was to reassess the mutation frequency of NF2, especially when combined with very high resolution array-CGH analysis of these tumors.

When the mutation frequency is small, these hubs suppress all mutations and gene product concentrations do not change, thus, the pattern is stable.