Sentence examples for mutation frequency observed from inspiring English sources

In summary, the overall distinctiveness of the regenerant mutational molecular spectrum (SBSs and indels) implies that the elevation in mutation frequency observed in regenerant plants cannot simply be attributed to an accelerated accumulation of the same kinds of mutations as arise spontaneously in sexually propagated plants.

Furthermore, it results disturbing that the increase in the mutation frequency observed due to C6SSR431- and G5C6SSR426-localized mutagenesis, was produced in strains that were already stable hypermutators.

The low mutation frequency observed for TP53 on sample tissues where other genes show higher values confirms that genes may be differently affected by background genetic noise.

We expected to find a relatively high mutation frequency due to HCV's high genetic plasticity, but contrary to our expectations, the 0.9% mutation frequency observed in the samples was relatively small in relation to the variability among independent HCV isolates (10 12%), and was in the range of quasispecies variability typically found in a given individual (∼1 4%).

Remarkably, the frequency of RifR for the H2O2-treated mutS dinB strain (3.3±1.9×10−6) was more than 6-fold lower than the spontaneous mutation frequency observed for the same strain following mock treatment (21.5±4.5×10−6), resulting in an overall negative value for H2O2-induced mutation frequency (−18.2±4.7×10−6; Fig. 3B).

The average mutation frequency observed in that study was 1.6 × 10−5 (Jander et al. 2003).

The distribution of mutation frequencies observed for a given spot in the control arrays was assumed to be noise for all non-wild type nucleotides.

We share Werngren's surprise at the extraordinary mutation frequencies observed for the Beijing strains.

Proposedly, the zebrafish mutation load is the maximum that is compatible with viability, a suggestion that is corroborated by comparable maximal mutation frequencies observed in C. elegans [ 13] and Arabidopsis [ 14].

However, in Δ yfh1, a rapid increase in the mutation frequency was observed 30 min after transition to aerobiosis (Fig.  3A), in agreement with the increase in ROS levels and DNA-strand breaks observed.

Moreover, in our experiments, we used different polymerases with different error rate (see M/M) and no significant differences in mutation frequency were observed, arguing against the generation of the mutations during PCR amplification.