Adequate mutation frequency was, however, achieved through treatment of developing rice zygotes on the panicle immediately after pollination [ 29].
Surprisingly, cells overexpressing KDM4D show also significant increase in the mutation frequency (32.5 fold increase), however it is at least 15 fold less than the increase observed in cells overexpressing KDM4A-C fusions (Table 1).
However, the mutation frequency of the NC4 spores formed in space was similar to that of the ground control.
However, the mutation frequency of this recombinant virus (HSV-2 6757PR) was not completely penetrant when compared to the parental HSV-2 6757 virus, which showed a 400-fold higher percent of resistant mutants compared to HSV-1 SC16.
However, the mutation frequency in the hyper-IgM syndrome (usually <2%) (Chu et al, 1995; Monson et al, 2001; Weller et al, 2001) is below the cutoff level used to distinguish between mutated and unmutated CLL cases.
However, the mutation frequency in adenocarcinomas were similar to those reported in the studies of Saber et al [ 20] and Yom et al [ 21], but it is lower than in a study by Frattini et al [ 23], who reported of a frequency of 50%% in 17 intestinal type adenocarcinomas from Italian patients.
4 7 However, data concerning mutation frequency of the RAS mutations other than KRAS exon 2 are very limited.
However, the accurate mutation frequency can not be measured because of the existence of SNP bands (about 1000 and 500 bp, Figure 2B).
However, the high mutation frequency combined with the ability to screen individual targets allows one to screen homeologs or gene family members individually and then combine the mutant alleles through breeding.
However, comparison of the mutation frequency in the diagnostic (seven mutations in 93 children (7.5%)) and remission samples (four mutations in 42 children (9.5%)) suggests little difference.
