Sentence examples for mutation frequency caused from inspiring English sources

The increase in the mutation frequency caused by the loss of the DNA repair activity may be an advantage for these pathogens that need to adapt to a frequently changing environment.

On the other hand, mutation frequency caused by radiation and chemical mutagenesis range from 1.0×10-3 1.0×10-30-3 atospecific loci when in vivo spermatogonial treatments were carried out in zebrafish and medaka [ 2- 4].

Previous studies have suggested that H2O2 affected KatG mutation frequency and caused changes in resistance to isoniazid (INH) (Timmins and Deretic, 2006).

Mutations and selection might occur with an increased frequency caused by the toxic radicals produced in phagocytic cells.

Likewise, high mutation frequencies have been suggested as the cause of the frequently acquired antibiotic resistance during treatment of H. pylori infections (Bjorkholm et al., 2001).

Therefore, the low KRAS mutation frequency of HNSCC may cause difficulty in predicting the effect of cetuximab and other EGFR inhibitors.

We analysed the nature of SNPs that define clusters and found C➝T/G➝A transitions were the most frequent polymorphisms in both 18S and ITS1 sequences, likely to be a consequence of high frequency mutations caused by deamination of methyl cytosine to thymine (Additional file 3).

In mouse models, lack of functional DNA MMR causes increased spontaneous mutation frequency rates in all parts of the colon [46] and enhances somatic mutation of Apc and p53; genes mutated in the majority of colorectal cancers [47].

The results suggest that this high mutation frequency of the mutation is likely to cause a high prevalence of phenobarbital-resistant epilepsy in Border Collies.

Expression of hEndoV in E. coli cells deficient in nfi, mug and ung genes caused 3-fold reduction in mutation frequency [ 16].

Accordingly, H2O2 treatment causes a considerable increase in mutation frequency.