Sentence examples for mutation frequencies the from inspiring English sources

To calculate mutation frequencies, the accumulated number of unique mutations were divided by the theoretical maximum number of the corresponding type of mutation so as to correct for base composition [30].

The genetic model is therefore fully specified by the BRCA1 and BRCA2 mutation frequencies, the polygenic variance and genotype-specific incidences for each type of disease.

Most of the pieces have low mutation frequencies: the fraction of the pieces with mutation frequencies <50 pmg (F < 50) is 76% (these pieces are colored light or dark gray in Fig.  3).

The individual mutation frequencies (the number of times a mutation is observed divided by the size of the M1 population) (Jander et al. 2003) ranged from 2.5 × 10−3 for dms4-1s1 to 5.7 × 10−4 for dms4-1s4.

A significant association was found between smoking history and EGFR pathway gene mutation frequencies: the proportions of smoking vs non-smoking in E746_A750del, L747_A750>P, L747_T751del, L747_P753>S, T790M, L858R and G12C mutations were significantly different with the proportion of smoking vs non-smoking in the overall sample (P⩽0.001).

In Figure  3, we show the spatial distribution of the ACH mutation frequency with different colors representing the different mutation frequencies: the highest frequency is colored dark red and the lowest frequency is colored light gray.

Mutated genes in each patient are ranked by mutation frequency; the median mutation frequency over all patients is plotted for each percentile.

Successful TILLING not only depends on the population size and the mutation frequency, the method used to identify specific mutations in the population is equally important.

The mutation frequencies of the infected plants and the spontaneous mutation frequencies of the control plants were compared.

The mutation frequencies in the mitochondrial genome of the three mouse genotypes were compared using Fisher's exact test.

The mutation frequencies of the gpt gene in the cortex and inner and outer medullae were unaffected by OTA treatment.