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Mutation frequencies and the structure of mutated DNAs in these conditions were compared.
high mutation frequencies.
medium mutation frequencies.
After the flight, DNA replication and mutation frequencies were measured.
Two different concentrations of template DNA were used, according to the manufacturer protocol, for the generation of medium mutation frequencies (MMF) and high mutation frequencies (HMF).
Relative mutation frequencies were analyzed using a reporter plasmid that allowed direct comparison of the methods.
Particular concerns arise for RNA viruses, which exhibit high mutation frequencies.
Point mutation frequencies were measured in a BY4741 background.
Mutation frequencies were determined as previously described [56].
Mutation frequencies can be determined via fluctuation analysis [45].
Genes with co-occurring mutations tend to have similar mutation frequencies, whereas genes with anti-co-occurring mutations tend to have different mutation frequencies.
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