Sentence examples for mutation fraction from inspiring English sources

Likewise, high mutational heterogeneity and subclonal mutation fraction can lead to increased likelihood of tumor recurrence.

A mutation probability and a mutation fraction are set by the designer as a design parameter.

A suitable calculation of maximal driver mutation fraction will approximate but not exceed the fraction of cancer nuclei.

The results of the titration series revealed that the detected mutation fraction was highly variable in both samples when the template input was less than 379 copies.

Particularly, given one sample, the maximal mutation fraction of all drivers is separately calculated based on three approaches: MAF, piecewise MCF, and Hill function MCF.

x -axis indicates the fraction of CD19+CD5+ cells assessed by FACS analysis, and y -axis indicates the maximal mutation fraction of all targeted driver genes of each sample calculated by different methods.

For each mutation, mutant fractions as low as 10−5 were detected, indicating that this assay can be used on a variety of base substitution mutations.

These suggest using phenotypic mutation fractions that increase algebraically with the genomic mutation rate μ.

However, with the cotreatment of DPE and UVA, the mutation fractions of AL cells showed a dose-dependent increase.

The functional dependence of the phenotypic mutation fractions with μ is of the same type as observed in an optimized population, Eq. (6).

As shown in Figure 2, the mutation fractions induced by DPE (20 μg/mL) or UVA (0.5 J/cm) alone were 73 ± 27 and 73 ± 20 mutants per 10 survivors, respectively.