Sentence examples for mutation for a from inspiring English sources

The high recurrence of RETR114H in Chinese HSCR patients lead us to investigate whether its frequency is due to a possible mutational hot spot (i.e. arisen independently) or, perhaps, a possible founder mutation for a sub-population of HSCR patients whose significance is not yet known.

(Testing negative for these, however, would not guarantee that she's in the clear, because not every mutation for a given gene is on the list).

We tested this idea by immunizing Ig μ transgenic mice in a manner designed to select B cells that required only one VH mutation for a switch in antigenic specificity and recruitment into the memory pool.

Recessive means that both parents need to pass a genetic mutation for a child to develop the disorder.

In conclusion, we have identified a translationally silent variant in a potential exonic splice enhancer of the bovine MFN2 gene as the causative mutation for a splice defect.

Thus either the mutation is in fact a founder mutation for a sub-population of Chinese HSCR or more than one carrier has introduced the mutation into the Chinese population given its relatively young age.

It's hard to argue that ethnicity is an empty concept when one gene mutation for an iron storage disease, hemochromatosis, affects fewer than 1percentt of Armenians but 8 percent of Norwegians.

There were 15 patients with KRAS G12C and 1 patient with KRAS G12V mutation for an overall mutation rate of 18.6%.

Thus, local adaptation to conditions surrounding LA seems a more plausible explanation than biased mutation for an excess of loci with highly positive α values.

For cases diagnosed above age of 60 years the ORs were 2.4 (P=0.0009) for NBS1 mutation, 1.8 (P<0.0001) for a CHEK2 mutation and 0.7 (P=0.6) for BRCA1 mutation.

The ORs for early-onset prostate cancer were 3.1 (P=0.003) for NBS1 mutation, 2.3 (P<0.0001) for a CHEK2 mutation and 1.9 (P=0.9) for a BRCA1 mutation.