Sentence examples for mutation explained by from inspiring English sources

In Norwegian White Sheep (NWS), two myostatin (MSTN) mutations affecting conformation and fat classes are segregating: the 3'-UTR mutation creating an illegitimate microRNA site (c.2360G>A) that was identified in Texel sheep [ 1] and a frameshift mutation explained by a deletion of one base pair in nucleotide position 960 (c.960delG), identified in NWS [ 2].

(A ) The fraction of (log) viral fitness variation explained by deleterious mutations over time for the simulation whose phylogenies are plotted in Figure 6.

The rare events of regional shifts in the mutation pattern between closely related species, such as mouse and rat or human and chimpanzee, have primarily been related to a bias in GC→AT versus AT→GC mutation rate explained by either a regional mutation bias or a biased gene conversion, leading to dispersing evolution in GC content (Cooper et al. 2004; Ebersberger and Meyer 2005).

This extreme haplotype heterogeneity indicates that R116W is a recurrent mutation, maybe explained by the high mutability of CpG dinucleotides.

Relatively often, a novel mutation is explained by a local DNA sequence change, affecting one or a few adjacent nucleotides.

The greater severity of the T158M mutation is explained by more extreme destabilization of the protein, coupled with reduced affinity for modified DNA.

However, most of the increase in their mutation rates is explained by the high mutation bias of the {C > G | 1, CG} context itself.

Since the recurrence of the c.833T>C mutation cannot be explained by any known mutational hotspot in the vicinity of c.833T, a different mutational mechanism should be considered.

Such a pattern of changes that involves multiple mutations could be explained by an initial deleterious mutation compensated by selection on subsequent mutations that restored the identity of the S residue.

The latter results concerning ACVR1 mutation can be explained by the segregation of this alteration with H3.1-K27M H3.1-K27Mrather than the reverse.

We confirmed that the nudE nonsense mutation explains the 11R2 phenotype by showing that germline clones of nudE 39A, a previously described null allele (Wainman et al. 2009), also fail to specify an oocyte.