Sentence examples for mutation exhibit increased from inspiring English sources

Notably, melanomas that have the V600E BRAF mutation exhibit increased HIF-1α expression.

In contrast, Atm knock-in heterozygous mice harbouring an in-frame deletion corresponding to the human mutation exhibit increased susceptibility to a wide variety of tumours [ 14].

Strikingly, a cancer-associated mutation exhibited increased basal activity and failed to rescue the embryonic developmental phenotype in transgenic worms.

Variable dependence on S1 cleavage also extends to T-ALL-associated NRR mutations, as common class 1 mutations display variable decrements in ligand-independent activation when introduced into furin-resistant receptors, whereas a class 2 mutation exhibits increased signaling activity.

G2019S pathogenic mutation exhibits increased kinase activity and is phosphorylated to wild-type (WT) levels at Ser910/935/955/973.

Endothelial cells from patients with mutations exhibit increased proliferation and an inability to form vascular networks (9).

Mice homozygous for the Tll2 mutation exhibit increases in muscle mass, but these increases are relatively small compared to those seen in either Mstn /– or MstnD76A/D76A mice.

Moreover, the effect of the point mutation was dose-dependent, with mice heterozygous for the mutation exhibiting increases of 14 19% and mice homozygous for the mutation exhibiting increases of 60 99% compared to wild type mice.

Notably, cancer cells carrying mutations in BRCA1/2 exhibit increased sensitivity to topoisomerase inhibitors.

As demonstrated in the current study, the R225Wγ3 mutation in humans is a gain-of-function mutation that exhibits increased basal and AMP-activated activity of AMPK.

Plants containing mutations in ANT genes exhibit increased sensitivity to disruptions in polar auxin transport [ 77], suggesting that its role during embryogenesis might be related to auxins.