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Exact(11)
Notably, each point mutation (except for Arg117Gly) revealed similar relative kinase efficacy whether co-transfected with wild-type Chk2 or not (Figure 3 and 4).
On a protein-coding gene sequence, all positions should be affected by both selection and mutation, except for four-fold third codon positions.
U85 is tolerant to mutation, except for U85A.
We did not detect genetic alterations in cells cultured after the elimination of cells showing IDH1 mutation, except for one case.
All 7 patients with DNMT3A mutations harbored single mutation, except for one patient who showed both K219R and R736H mutations simultaneously.
Also, the sites where the translation stop codon was observed showed no other mutation, except for one clone from patient RF145, which showed a mutation in aa 447.
Similar(49)
Therefore, their mutations, except for mutating to glycine or proline, will lead to negligible interference in the folding of the protein.
As a rhEPOR ligand, engineered rhEPOR containing four amino acid mutations (EPORm4L) was constructed by integration of mutations except for H114Y.
For example, tumors typically have from 30 to 80 single-base mutations, except for types that take less time to develop such as leukemia (about 10 mutations).
SMs were characterized by chromosomal rearrangements resulting in activated kinase signaling in 40%, and an absence of TERT-p mutations, except for the one SM that succumbed to hematogenous metastasis.
Namely, all mutations except for 309+C in region 35 464 match sequence no.
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