Sentence examples for mutation events is from inspiring English sources

The youngest splits in the tree (common ancestors for haplotypes 6 7 and 60 61) were dated even closer to the LGM: with a mean of 29 34 ka (1 76 ka) from the coalescent estimation in BEAST; when based on the mutation rate of 7.6% per site per Ma (for transitions in third-codon positions of cytochrome b in Littorina [28]), the average time for these mutation events is 33 ka.

This is illustrated by Figure 2. Another aspect of the mutation events is that the gene variation at SNPs increases the frequency of a certain motif and leads to changes in gene expression.

The probability that the two FGF5 l-poitou and FGF5 l-donkey alleles could have independently arisen in several breeds as a consequence of distinct mutation events is very low.

For example, if a role for de novo mutation events is suspected, it will be extremely useful to sequence related individuals (48– 50) and, if the identification of individuals who are homozygous for rare loss-of-function alleles is desired, sequencing of individuals with evidence of inbreeding will be appealing (27).

In summary, our method reported in this study is a valid alternative to be considered for generating Drosophila mutants with a reasonable efficiency and as little time and effort as possible, especially when the prevention of delayed mutation events is preferred to reduce the off-target effects and mosaicism.

Where haplotypes establish but do not substantially move the marker frequency (see, for example, the event at generation 162 in the blue population), or where multiple similarly fit haplotypes establish in the same marker population, the number of mutation events is undercalled by the inference method.

Our TALEN approach appears to be highly efficient: targeted mutation events were detected in 50% of all transformants obtained, whereas 21% of the transformants were found to be bi-allelic knockout lines.

The relative ratio of recombination events versus mutation events was then determined.

Two distinct mutation events were first reported in C. pipiens and C. quinquefasciatus species [5].

Since independent mutation events are very unlikely to hit the exact same nucleotide site, each observed mutation should be found in only a single mutant strain.

No other mutation events were included in the model.