Sentence examples for mutation estimated to from inspiring English sources

One of the frameshifts was detected in the same position as a mutation estimated to be responsible for 40% of all male breast cancer cases in Iceland.

Moreover, the authors have observed in these patients a common haplotype, suggesting a founder mutation, estimated to have taken place about 2,400 years ago [ 13].

However, whether rare ATM mutations, estimated to be present in about 0.4%1%% of the population [ 8, 51], confer an increased breast cancer risk in the population, is beyond the scope of this study and has not been evaluated at a large scale in other studies yet either.

The mutation frequency for BRCA2 mutations was estimated to be 0.068% (95% CI: 0.033 0.141%).

MET mutation is estimated to be present in 5 21.6% of sporadic pRCC [ 8, 108, 139, 141].

This inversion mutation was estimated to have occurred 580,000 years ago (Wallace et al. 2011).

The penetrance for gastric cancer among individuals with a CDH1 mutation is estimated to be about 40%.

Nucleotide sequence divergence levels were less than 1% and the relative rate of recombination to mutation was estimated to 1.1 for the genome overall.

The F128A mutation was estimated to reduce the binding affinity of PR70 by fourfold, but retained 60% of the PR70 activity to enhance Cdc6 dephosphorylation.

The prevalence of G6PD genetic polymorphism (Viangchan mutation) was estimated to be below 1.5% in both males and females (33), with no difference between ethnic groups.

When a patient is referred to the CGC, DNA testing will be offered when the probability of being a carrier of a BRCA1 and/or BRCA2 mutation is estimated to be over 10% by the clinical geneticist.