Sentence examples for mutation enhanced the from inspiring English sources

The G2019S mutation enhanced the association between LRRK2 and actin-regulatory proteins that control chemotaxis.

In E. coli TC44, mutation of the poxB gene, which encodes pyruvate oxidase, was most beneficial for growth and pyruvate production, as the mutation enhanced the NAD+ concentration in the cells and activated several enzymes involved in the glycolysis pathway.

When we compared the DNA binding of nuclear extracts from HeLa cells transfected with wild-type and the S369-S373-S377 mutant Runx2 by EMSA, the mutation enhanced the specific Runx2-DNA binding (Fig. 4G).

The abundance and activity of the G1 cyclin Cln1/2 is required for polarization, cell elongation and transcriptional activation of FLO11, whereas Δcln3 mutation enhanced the filamentous growth [41].

Interestingly, only 12±2.7% of the homozygous lark1; E74BG01805 double mutants survived to the early pupal stage; i.e., most of them died prior to or at the third-instar larval stage, indicating that the BG01805 mutation enhanced the lethal phenotype of lark1.

However, AMBRA1 mutation enhanced the interaction between BECN1 and PIK3C3 within the Atg14-containing PIK3C3 complex.

It is important to compare the neurovirulence between the pre-epidemic FSS13025 and epidemic PRVABC-59 strains, and to determine whether the NS1 A188V mutation enhances the neurovirulence.

Indeed, this is the picture Zhu et al. observed for an SIV strain that harbours a mutation enhancing the expression of spikes at the virus surface.

Brown, J. T., Yang, X. & Johnson, A. W. Inhibition of mRNA turnover in yeast by an xrn1 mutation enhances the requirement for eIF4E binding to eIF4G and for proper capping of transcripts by Ceg1p.

HPLC quantification of the electrochemically produced metabolites showed that E158K mutation leads to an impairment of N-oxygenation activity while E308G mutation enhances the same activity.

We propose that the Tyr195Cys mutation enhances the interaction with Ca2 + and affects the packing of the Ca2 + binding loop, consequently increasing protein stability.