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Eqn (1) allows us to calculate a fitness value for each node in any of the 120 mutational paths, provided that the mutation effects on the properties are known.
"Network analysis of differential Ras isoform mutation effects on intestinal epithelial responses to TNF-α." Integr Biol (Camb) 5, no.
Therefore, certain protein-protein pairs may require careful adaptation of the positions of encounter and transition states when interpreting mutation effects on kinetic rates of association and/or dissociation.
This dependence of the mutation effects on the degree of adaptation of populations led to the theoretical prediction that mutation rates would be reduced in constant environments, in which the population has had enough time to adapt.
To facilitate the comparison of mutation effects on the cellular heme c levels, relative heme c levels of in each mutant were presented as the ratios of the absolute amount of heme c of each mutant vs. MR-1 under the same growth conditions (Fig. 1B).
What is the distribution of mutation effects on the adapters?
Similar(38)
the mutation effect on phenotypic expression and biodiversity generation (questions 12 and 18); and.
The mutation effect on Rev structure, which is destabilization of the protein structure, is manifest as a dramatic reduction in Rev activity in CAT-based assays.
For the essential checkpoint proteins, Mad2 and Cdc20, we present the mutation effect on our model in detail in Figure 4 for the Convey variant.
Data on the ADRB3 gene mutation effect on lipid metabolism are inconsistent and heterogeneous.
In short, the mutation effect (on the x-axis) for Enterobacteria phage If1 is underestimated in Figure 4, which does not take local strand asymmetry into consideration.
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