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(C ) Deaminase mutations relative to the TATA or TATA-like element for each RNAP II promoters (Rhee and Pugh, 2012 ) compared to the mutation distance distribution aligned to the transcription start site (TSS).
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The modifications were as follows: first, mutation distance d was distributed obeying binomial distribution; second, the selection process obeyed the natural selection protocol; third, ruggedness was introduced to the landscape according to the NK model; fourth, a noise was included in the fitness measurement.
The distribution of inter-somatic mutation distance in primary and metastatic tumors of sample D473 were compared to the distributions of inter-somatic mutation distances in HCC and other types of tumors, using published data downloaded from ICGC (ftp://data.dcc.icgc.org/version_11/).
To further investigate the inter-somatic mutation distance, we compared the inter-somatic mutation distances to the simulated null distributions.
Secondly, the mutation distance is added into the mutation operator to better control the mutation progress and avoid any narrow local optimization.
Figure 2 Atom-pair distance distribution.
We consider the problem of bounding the distance distribution for unrestricted block codes with known distance and/or dual distance.
Two subjects, A and PO, demonstrated distinct patterns for gag and env distance distribution, suggesting transmission of a single variant based on the gag distance distribution, but two viral variants were evident from the distribution of env distances.
We also compared distance distributions for the datasets of less and more than 125 sequences (see Methods) with the distance distribution of randomly selected non-coevolved site pairs.
We computed the inter-somatic mutation distance within individuals by defining the inter-somatic mutation distance as the distance from a somatic mutation to the very next one.
Their occurrences were examined for distance distribution within the range.
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