Sentence examples for mutation detection method from inspiring English sources

We developed a closed-tube HRM mutation detection method specific for SLC26A4 that can be used in the clinical diagnostic setting.

A novel RNA-templated single-base mutation detection method based on T4 DNA ligase and reverse molecular beacon (rMB) has been developed and successfully applied to identification of single-base mutation in codon 273 of the p53 gene.

Accordingly, in Table 1 the studies are ranked for sensitivity of the mutation detection method.

To our knowledge, this notion is currently not considered in any published somatic mutation detection method.

A novel PCR-based mutation detection method has been developed by Transgenomic.

The proportions of ATM heterozygotes were determined using the denaturing gradient gel electrophoresis mutation detection method.

This has potential to severely compromise clinical genomic utility, as indels are a major class of pathogenic variant, and are routinely and robustly detected by pre-NGS mutation detection methods, such as Sanger sequencing.

In addition, high sensibility mutation detection methods were also developed to perform a mutational screening study for the most frequent EGFR activating mutations.

Whole-exome sequencing and targeted NGS are the preferred methods for screening of PCC/PGL, both having precise mutation detection methods and low costs.

Translation of these mutations-disease biomarkers into clinical diagnostics yet requires simple, rapid, and cost-effective mutation detection methods that have high multiplexing ability and cross-platform compatibility [2].

Concerns with tumour heterogeneity underscore the importance of using highly sensitive mutation detection methods.