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For the first analysis, which used the most up-to-date growth rate estimated, the mutation density depicted a peak at ∼11 12 generations for RETR114H.
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@Adrianopoliz.
We estimated the mutation density based on Greene et al. [20] to 1 mutation every 573 kb.
The remaining population had a mutation density of ~1/550 kb.
A total of five mutations were identified resulting in a calculated mutation density of 1/526 kb.
This mutation density is well suited to high-throughput mutation discovery.
We estimated an overall mutation density of 1 mutation per 40 kb screened.
A high mutation density (1 mutation per 74 kb) was achieved by repeating the EMS treatment.
We estimated the SMART average mutation density to one mutation every 480 kb.
The frequency of mutations, mutation density and type of mutation also did not differ by gender or race.
Variation operators: recombination and mutation, as depicted below.
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