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For example, a mutation could cause an individual fish to have a slightly smaller body size than other individuals in the population.
The results suggested that F1174V mutation could cause two important secondary structure alterations, which led to the local conformational change in ALK kinase domain.
As looping can be interpreted as a deficiency in body balance, the lhx2 gene mutation could cause looping by affecting the vestibular system.
All of these suggest that OPA1 mutation could cause multiple organ abnormalities [17] and that analysis of the major organ systems may extend our knowledge of the clinical manifestations of OPA1 mutations.
We hypothesize that the mutation could cause a mechanism of non- stop mRNA decay.
Why EIF2AK4 mutation could cause abnormal angiogenesis in lungs in PCH patients remains unknown.
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These new mutations could cause a modification of the mutational landscape and reveal new pairs of SL, of course only in the treated patient sets.
Taken together, these facts strongly suggest that null SC5DL mutations could cause RG syndrome in humans.
Thus it is also possible that lam mutations could cause a form of premature senescence in Drosophila.
We also expect that the contributions of different proteins to a given phenotype are likely to vary: whereas one protein might be absolutely central to that phenotype, such that a large fraction of amino acid mutations could cause the phenotype, in a protein that participates in only part of that function, perhaps only a small fraction of mutations could cause that specific phenotype.
Although these may account for a relatively small percentage of all PD cases, analysis of the pathogenetic mechanisms involving these mutations may provide insights into the pathogenesis of idiopathic PD, it is also possible that different mutations could cause PD via different mechanisms.
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