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These combined results demonstrate that the G468-T transversion is dysfunctional and further indicate that AMPD1 alleles harboring this mutation contribute to the high incidence of partial and complete myoadenylate deaminase deficiency in the Caucasian population.
As the difference, or genetic distance, increases, the two separated populations may become distinct, both genetically and phenetically, although not only genetic drift but also natural selection, gene flow, and mutation contribute to this divergence.
It showed that both, mosquitoes with and without the L1014S kdr mutation, contribute to the malaria transmission.
It is likely, however, that genetic, epigenetic or other biological factors in addition to CTNNB1 mutation contribute to the pathogenesis of ACP.
It is also critical to determine the mechanism by which G34 mutations influence SETD2 function and how they and the K36M mutation contribute to tumorigenesis.
For instance, studies will be needed to address whether elevated levels of APOBEC3B-enabled mutation contribute to the development of drug resistance and metastases.
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How the mutation contributes to Crohn's disease is unclear.
It can be applied to sequential data prediction in transportation disruption or mutation, contributing to the prediction of transportation disruption.
Studies suggest that IDH mutation contributes to tumor pathogenesis through mechanisms that are mediated by the neomorphic metabolite of the mutant IDH1 enzyme, 2-hydroxyglutarate (2-HG).
The el1 mutation contributes to early flowering in japonica rice under long days but fails to limit GA signaling, thus negatively affecting spikelet fertility, which results in a loss of grain yield.
This finding strongly suggests that GAMYB expression and/or GA signaling is controlled normally in Koshihikari, although the el1 (type 3) mutation contributes to the early flowering of Koshihikari under long-day conditions in temperate regions.
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