Sentence examples for mutation context from inspiring English sources

Mutation context of CanR transformants expressing APOBEC3G and AID.

Mutation bias indicates the total excess (or deficiency) of mutations within a given mutation context.

We denote the mutation context of mutation mut in position pos of the word W as { mut | pos, W}.

Together, the increase in these two mutation types matches signature 10 from a recent characterization of trinucleotide mutation context [ 45].

KLLN promoter methylation modified the risk of specific non-malignant CS phenotypes dependent on the PTEN mutation context.

DOI: http://dx.doi.org/10.7554/eLife.00534.009 10.7554/eLiFigure3 figureigure 3—figure supplement 1. Mutation context of hyperactive APOBEC3G and AID are identical to the wild type proteins.

These mutation contexts are hypermutable in H. sapiens.

Also, several mutation contexts are hypermutable in M. musculus but not in H. sapiens.

These word frequencies were used in our calculations of mutation bias and minimal contrast for mutation contexts in M. musculus.

A comprehensive analysis of mutagenesis in 4 bp mutation contexts requires a vast amount of mutation data.

Namely, we found that the aforementioned hypermutable human mutation contexts except for the excess of C > T mutations in the CG context are not hypermutable in M. musculus.