Sentence examples for mutation constituted the from inspiring English sources

The resulting networks of co-occurring genetic changes were visualized as undirected node-and-edge graphs by making use of the Rgraphviz package in Bioconductor for R. Thirty-three female breast cancer patients carrying the same 999del5 BRCA2 germline mutation constituted the study group analyzed with array CGH (comparative genomic hybridization).

Biochemical, cellular and functional analyses of a number of SI mutations constituted the basis for a classification of these mutants into seven phenotypes depending on the intracellular localization and function of SI [9] (Table 1).

The examples of 6,480 deleterious mutations and 1,637 neutral mutations constituted the initial knowledge base.

The set of identified point mutations constituted the input genotype data for GWAMAR.

In most heterogeneous tumors, cells with all mutations constituted the major population (Table  1).

Expression levels of PIK3CA, the oncogene bearing the highest number of mutations in breast cancer, were therefore mostly stable in breast cancer subgroups indicating that mutations constituted the main tumor change affecting PIK3CA.

Mutations constitute the main source of genetic diversity in asexual populations.

Finally, the fact that we have observed in the networks a fairly strong founder effect with a small cluster of haplotypes (separated by single step mutations) constituting the vast majority outside Africa provided further evidence for absence of recombination.

These mutations constitute the genotype data.

The remaining 1,637 neutral mutations constitute the negative examples.

Of these, 6,480 deleterious mutations constitute the positive examples.