Sentence examples for mutation conferring a from inspiring English sources

In 1998, a second mutation conferring a congenital deficiency in leptin was described in three individuals from a consanguineous Turkish pedigree [15].

Sequencing of exons revealed a single point mutation conferring a T to A transversion in the fourth exon at 536 bp from the ATG start site causing the 179th amino acid to change from an isoleucine (I) to an asparagine (N) (179N).

Nevertheless, an M133T mutation conferring a novel N-linked glycosylation site could efficiently rescue virion secretion of the G145R mutant, and to a lesser extent, of several other immune escape mutants.

In fact, the identified phytoene synthase 1, which catalyzes a rate-limiting step in the carotenoids pathway, corresponds to the locus " r" [ 34] that carries a recessive mutation conferring a characteristic yellow flesh phenotype.

QRDR sequencing showed gyrA mutations resulting in a serine to tyrosine substitution at codon 83 and an aspartic acid to asparagine substitution at codon 87, and a parC mutation conferring a serine to isoleucine substitution at codon 80. *PFGE, pulsed-field gel electrophoresis.

The triple mutation confers a three-fold increase in sensitivity to ciprofloxacin in vitro and similar sensitivities to a range of other quinolones.

This mutation confers a poor prognosis in the metastatic setting, and a high risk of cancer recurrence as seen in several studies [6 9].

The R1902C autism mutation conferred a Ca(2+ -dependent conformational change in Nav1.2+ -dependentconformationalat was absent in the wild-type changex.

On the contrary, the Y143R mutation conferred a decreased sensitivity to RAL (FC = 2).

(e) All mutations are 'equal' such that no mutation confers a survival advantage or disadvantage to the cell harboring it.

The dbf4-ΔN221 dbf4-ΔN221onfers a domutationheconfers bypass.