Sentence examples for mutation conferred a from inspiring English sources
Thus, these two mutations demonstrated reciprocal host range phenotypes involving different regions of C. The CΔ170 mutation conferred a significant level of attenuation in hamsters and AGMs that closely resembled that of CF170S and will be of particular utility for vaccine development because it involves a deletion of six nucleotides rendering it highly refractory to reversion.
The R1902C autism mutation conferred a Ca(2+ -dependent conformational change in Nav1.2+ -dependentconformationalat was absent in the wild-type changex.
On the contrary, the Y143R mutation conferred a decreased sensitivity to RAL (FC = 2).
However, when the experiment was repeated using wild type M. tuberculosis H37Rv and a M. tuberculosis hspR KO mutant [27] the mutation conferred a growth defect relative to the wild type strain during the batch phase of growth whereas there was no additional reduction of fitness observed during chemostat culture at slow growth rate (Figure 4).
The presence of the plasma 249ser TP53 mutation conferred a statistically significant almost 4-fold increase in risk of cirrhosis in this population.
In the related Semliki Forest virus, a corresponding mutation conferred a replication advantage in cholesterol-depleted insect cells (24 ), which for the virus would implicate an advantage in its reservoir.
A codon 93 nonsense mutation conferred an intermediate 130R,160S phenotype (Fig. 4D).
The triple mutation confers a three-fold increase in sensitivity to ciprofloxacin in vitro and similar sensitivities to a range of other quinolones.
In 1998, a second mutation conferring a congenital deficiency in leptin was described in three individuals from a consanguineous Turkish pedigree [15].
This mutation confers a poor prognosis in the metastatic setting, and a high risk of cancer recurrence as seen in several studies [6 9].
(e) All mutations are 'equal' such that no mutation confers a survival advantage or disadvantage to the cell harboring it.
