Sentence examples for mutation close to from inspiring English sources

Jiang, M. et al. A novel missense mutation close to the charge-stabilizing system in a patient with congenital factor VII deficiency.

*) mecC1 of S. xylosus S04009 does not encode a functional PBP2a due to a frameshift mutation close to the 5′ end of the gene.

Sequencing analysis of candidate genes involved in thyroid development revealed a new heterozygous mutation close to the transcription initiation site of the PAX8 gene.

The crystal structure of the BFPvvD8-NADPH complex has revealed that the increased fluorescent intensity of BFPvv is related to the conformational change caused by a Gly176 mutation close to the NADPH binding site (Kao et al. [2011]).

TNFR2 lies within the Idd9 interval, and the diabetes-associated variant contains a mutation close to the TRAF2 binding site.

Because the CI of the QTL was large (31 cM), we therefore selected 5 genes that effectively corrected the AF QTL (P > 0.1), and therefore likely to be controlled by the mutation sought or by a mutation close to it.

Comparing all four of the SSG mutageneses shown in Fig. 2, the frequency of incorporating mutations among the ura3Δ isolates was highest for the mutation closest to URA3 and lowest for the mutation farthest from this marker (Fig. 2, second column).

For 11R2, 19 of 48 femalesles had recombined between tester distal and proximal SNPs (SNP_61A and SNP_75F, respectively in Figure 2D); 3 of 13 recombinants with distal FRT2A homology (group 1) and 5 of 6 recombinants with proximal FRT2A homology (group 2) were mutant, mapping the mutation closer to 75F than to 61A.

The newly created R-enantioselectivity of the esterase mutein (ERapp = 1.5) has been further enhanced by a designed evolution strategy involving random mutations close to the active site.

Sulfolobus acidocaldarius β-glycosidase (BGAL_SULAC) was used as an extremophilic enzyme model to study the effect of mutations close to the catalytic residues on the enzyme activity and the pH-activity profile.

Additionally, point mutations close to breakpoint junctions are subjected to further examination during Sanger confirmation.