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The mutation characteristics are shown in Table 3.
The patients' demographic, clinical and mutation characteristics are shown in Table 1.
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Although, only one testis was examined in this work, no exceptional mutation characteristics were observed for this testis in comparison with other age-matched testes, analyzed for the Apert and MEN2B mutations (19).
TP53 mutation types and other tumor characteristics are listed in Table 1.
Epidermal growth factor receptor mutation status and patient clinicopathological characteristics are compared in Table 2.
The results of the assessment of the EGFR/PI3K/PTEN axis alterations and of the correlations between EGFR amplification, EGFR protein level, PIK3CA mutation, PTEN status and clinicopathological characteristics are summarized in Table 2.
No associations between KRAS mutations and histopathological characteristics were observed (Table 3).
Associations between treatment response and mutation status or baseline characteristics were assessed using the Fisher's exact test for dichotomous variables, or logistic regression for continuous variables.
The association of hepatitis B virus (HBV) genotypes and basal core promoter (BCP) and precore (PC) mutations with the clinical characteristics is increasingly recognized.
The probability that a proband with a given set of personal and family characteristics is a mutation carrier can be estimated from the model fit shown in Table 5. Start with a log odds score of θ = the baseline coefficient, -3.767.
Associations between mutations and clinical and biological characteristics were analyzed using a chi-square test or Fisher's exact test.
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