Exact(1)
Presumably then, a mutation changing an amino acid in the 7th trans-membrane region of a light-insensitive GPCR was involved in the acquisition of light sensitivity in animals.
Similar(7)
They may result from a mutation changing a sense codon into a stop codon or from the introduction into (or loss from) the reading frame of one or several nucleotides leading to a shift of translation frame.
Mutations changing a minor codon to a major codon, hence increasing the frequency of major codons within a gene, are known as "preferred" changes.
Another mutation changing Pro17 (c.49C > A, p.P17T) was reported in a Chinese family [ 6].
It follows that a mutation changing the reproductive value of a male will be selected more strongly than a mutation with identical effects in females., Recently, we studied the effects of polyandry on expected distorter frequencies, allowing viability selection to differ between males and females.
Such a pattern implies that a mutation changing the encoded amino acid sequence is much less likely to be different between two species than one which is silent.
Interestingly, a mutation changing alanine 302 to serine in the Tribolium GABA receptor is associated with cyclodiene resistance [ 23, 24].
For example, if a single causative mutation is segregating in an F2 population, our model predicts that the power of BSA-seq to detect a mutation changing the phenotype by 5% relative to wild type is greater than 0.9 for a total population size of 10, a 5% cutoff for phenotypic selection, and an average sequencing coverage of 25×.
Related(2)
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