Sentence examples for mutation carries a from inspiring English sources

19 Genetic mutations within the cyclin-dependent inhibitor 2A tumor suppressor gene on chromosome 9p21 accounts for 40% of hereditary melanoma and a known mutation carries a 76% chance of developing melanoma.

The participants in this study were prevalent cases and carrier frequency may be either underestimated or overestimated if male breast cancer associated with a BRCA1 or BRCA2 mutation carries a different prognosis from breast cancer in men without a mutation.

BRCA2 germline mutation carries an increased risk for cancers of the prostate, pancreas, gall-bladder/bile duct, and stomach, as well as for malignant melanoma [ 25].

Individuals heterozygous for the Factor VLeiden mutation carry a risk of venous thrombosis 5 7 times higher than in the general population.

The cell line Ma-Mel-53 and its corresponding tissue in addition to the codon 61 mutation carried a second N-RAS mutation at codon 68 (R68T).

We used human APP-Tg mice J20 overexpressing the familial AD-linked mutation carrying a mutant form of the human APP bearing the both Swedish (K670N/M671L) and the Indiana (V717F) mutations (APPSwInd) [16], imported from the Jackson Laboratory (USA).

We concluded that G6PD c.563C > T mutation carried a risk of early development of moderate hyperbilirubinemia in neonates.

Here we tested the hypothesis that women with an extremely high breast cancer risk (due to a BRCA1 mutation) carry a specific methylation signature in peripheral blood cells, which is also able to predict sporadic breast cancer incidence and death.

Results The recently described zebrafish dragonfish (dgf) mutant carries a mutation in enpp1.

Nine of 17 tumors (52.9%) with a mutation carried an amino acid changing mutation in the nicotinamide adenine dinucleotide dehydrogenase (NADH) complex.

Interestingly, all five examined astrocytomas of patients with Li-Fraumeni syndrome carried R132C IDH1 mutations, indicating that glial/glioma precursor cells with a germline TP53 mutation carry an increased risk to acquire such a non-R132H mutation [ 130].